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Localised ‘iron overload’ has been associated with several neurodegenerative diseases (i.e., Alzheimer’s disease and Parkinson’s disease), based on measurements of elevated brain iron, demonstrated through magnetic resonance imaging (MRI) imaging [23-25] , ferritin in cerebrospinal fluid (CSF) [26,27] , and postmortem analyses [28-30]

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Collectively, in the non-biofilm-infected diabetic chronic wound, Se-containing MN could reduce inflammation by scavenging RS, while promoting wound healing through collagen deposition and angiogenesis