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In a systematic review, for example — one of the earliest reviews involving dihexa, in fact — the authors had this to say about the peptide:4 “In models of cognitive deficit, eight of nine studies found Ang IV and its analogs (Nle1-Ang IV, dihexa , LVV-hemorphin-7) improved performance on spatial working memory and passive avoidance tasks.” “[Among Ang IV analogs,] Dihexa may be the most promising compound for testing in humans.” Later reviews echo the 2018 findings and dig further into how dihexa works